The 2019 U.S. Men's Clay Court Championships (also known as the Fayez Sarofim & Co. U.S. Men's Clay Court Championships for sponsorship purposes) was a men's tennis tournament played on outdoor clay courts. It was the 51st edition of the U.S. Men's Clay Court Championships, and an ATP Tour 250 event on the 2019 ATP Tour. It took place at River Oaks Country Club in Houston, Texas, United States, from April 8 through April 14, 2019.
See main article: 2019 U.S. Men's Clay Court Championships – Singles.
Casper Ruud, 7–6(7–4), 4–6, 6–3See main article: 2019 U.S. Men's Clay Court Championships – Doubles.
Santiago González / 
Aisam-ul-Haq Qureshi defeated 
Ken Skupski / Neal Skupski, 3–6, 6–4, [10–6]| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Steve Johnson | 39 | 1 | ||
 France | Jérémy Chardy | 42 | 2 | |
| United Kingdom | Cameron Norrie | 55 | 3 | |
| Reilly Opelka | 56 | 4 | ||
| Taylor Fritz | 58 | 5 | ||
| Mackenzie McDonald | 59 | 6 | ||
 Australia | Jordan Thompson | 67 | 7 | |
| Sam Querrey | 71 | 8 |
The following players received wildcards into the main draw:
The following players received entry via the qualifying draw:
John Isner → replaced by 
Marcel Granollers Nick Kyrgios → replaced by 
Paolo Lorenzi
Yoshihito Nishioka → replaced by Casper Ruud| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| Bob Bryan | Mike Bryan | 20 | 1 | |||
| Austin Krajicek |  New Zealand | Artem Sitak | 80 | 2 | ||
| United Kingdom | Luke Bambridge | United Kingdom | Jonny O'Mara | 93 | 3 | |
| United Kingdom | Ken Skupski | United Kingdom | Neal Skupski | 95 | 4 |
The following pairs received wildcards into the doubles main draw:
