| Date: | 23–29 September |
| Edition: | 13th |
| Draw: | 48S / 16D |
| Surface: | Hard |
| Location: | Tiburon, United States |
| Champs: |  Tommy Paul |
| Champd: | Robert Galloway /  Roberto Maytín |
| After Year: | 2022 |
The 2019 Tiburon Challenger was a professional tennis tournament played on outdoor hard courts. It was the thirteenth edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Tiburon, California, United States, between September 23 and September 29, 2019.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| United States | Tommy Paul | 88 | 1 | |
| United States | Denis Kudla | 107 | 2 | |
| United States | Marcos Giron | 125 | 3 | |
 Ecuador | Emilio Gómez | 166 | 4 | |
| Mikael Torpegaard | 167 | 5 | ||
| United States | Michael Mmoh | 168 | 6 | |
| Darian King | 170 | 7 | ||
 Australia | Thanasi Kokkinakis | 181 | 8 | |
 France | Enzo Couacaud | 187 | 9 | |
| United States | Christopher Eubanks | 190 | 10 | |
| United States | Mitchell Krueger | 192 | 11 | |
 Canada | Peter Polansky | 200 | 12 | |
 Colombia | Daniel Elahi Galán | 201 | 13 | |
| United States | Thai-Son Kwiatkowski | 209 | 14 | |
| United States | Ernesto Escobedo | 215 | 15 | |
| United States | Maxime Cressy | 228 | 16 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw using protected rankings:
The following players received entry from the qualifying draw:
See main article: article and 2019 Tiburon Challenger – Singles.
Tommy Paul def. Thanasi Kokkinakis 7–5, 6–7(3–7), 6–4.See main article: article and 2019 Tiburon Challenger – Doubles.
Robert Galloway / Roberto Maytín def. JC Aragone / Darian King 6–2, 7–5.
