| Date: | 21–27 October |
| Edition: | 1st |
| Location: | Hamburg, Germany |
| Champs: | Botic van de Zandschulp |
| Champd: |  James Cerretani / Maxime Cressy |
The 2019 Tennis Challenger Hamburg was a professional tennis tournament played on indoor hard courts. It was the first edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Hamburg, Germany between 21 and 27 October 2019.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Italy | Salvatore Caruso | 95 | 1 | |
 Sweden | Elias Ymer | 123 | 2 | |
| Italy | Gianluca Mager | 124 | 3 | |
 Ukraine | Sergiy Stakhovsky | 142 | 4 | |
| Italy | Alessandro Giannessi | 147 | 5 | |
| Italy | Federico Gaio | 150 | 6 | |
| Robin Haase | 151 | 7 | ||
| Oscar Otte | 155 | 8 | ||
 Serbia | Viktor Troicki | 160 | 9 | |
| Italy | Filippo Baldi | 163 | 10 | |
| Serbia | Nikola Milojević | 164 | 11 | |
| Rudolf Molleker | 167 | 12 | ||
 Spain | Pedro Martínez | 168 | 13 | |
| Tallon Griekspoor | 169 | 14 | ||
 Slovakia | Filip Horanský | 173 | 15 | |
| Spain |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw using a protected ranking:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
Vadym UrsuThe following players received entry as lucky losers:
Kacper ŻukSee main article: 2019 Tennis Challenger Hamburg – Singles.
Bernabé Zapata Miralles 6–3, 5–7, 6–1.See main article: 2019 Tennis Challenger Hamburg – Doubles.
James Cerretani / Maxime Cressy def. 
Ken Skupski / 
John-Patrick Smith 6–4, 6–4.
