The 2019 St. Petersburg Open was a tennis tournament played on indoor hard courts. It was the 24th edition of the St. Petersburg Open, and part of the ATP Tour 250 Series of the 2019 ATP Tour. It took place at the Sibur Arena in Saint Petersburg, Russia, from September 16 through 22, 2019.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Daniil Medvedev | 4 | 1 | ||
| Karen Khachanov | 9 | 2 | ||
| Matteo Berrettini | 13 | 3 | ||
| Borna Ćorić | 15 | 4 | ||
| Andrey Rublev | 37 | 5 | ||
| Mikhail Kukushkin | 56 | 6 | ||
| Adrian Mannarino | 59 | 7 | ||
| Casper Ruud | 60 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry using a protected ranking into the main draw:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Tomáš Berdych → replaced by 
Damir Džumhur
Laslo Đere → replaced by 
Matteo Viola Miomir Kecmanović → replaced by 
Jozef Kovalík
Corentin Moutet → replaced by Janko Tipsarević Salvatore Caruso| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| Nikola Mektić | Franko Škugor | 50 | 1 | |||
 Belgium | Sander Gillé | Belgium | Joran Vliegen | 94 | 2 | |
| Czech Republic | Roman Jebavý |  Austria | Philipp Oswald | 106 | 3 | |
 Brazil | Marcelo Demoliner | Matwé Middelkoop | 114 | 4 |
The following pairs received wildcards into the doubles main draw:
See main article: 2019 St. Petersburg Open – Singles.
Daniil Medvedev def. Borna Ćorić, 6–3, 6–1See main article: 2019 St. Petersburg Open – Doubles.
Divij Sharan / Igor Zelenay def. Matteo Berrettini / Simone Bolelli, 6–3, 3–6, [10–8]
