| Champ: |  Elise Mertens |
| Runner: |  Simona Halep |
| Score: | 3–6, 6–4, 6–3 |
| Type: | singles doubles |
| Draw: | 28 (4 / 4) |
| Seeds: | 8 |
| Before Name: | Qatar Total Open – Singles |
| After Name: | Qatar Total Open – Singles |
See main article: 2019 Qatar Total Open.
Elise Mertens defeated Simona Halep in the final, 3–6, 6–4, 6–3 to win the singles tennis title at the 2019 WTA Qatar Open.
Petra Kvitová was the reigning champion, but chose not to participate.
The top four seeds received a bye into the second round.
The top seed received a bye into the second round.