| Date: | 6–12 May |
| Edition: | 6th |
| Draw: | 48S / 16D |
| Prize Money: | €137,560+H |
| Surface: | Clay |
| Location: | Aix-en-Provence, France |
| Champs: | Pablo Cuevas |
| Champd: | Kevin Krawietz /  Jürgen Melzer |
The 2019 Open du Pays d'Aix was a professional tennis tournament played on clay courts. It was the sixth edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Aix-en-Provence, France between 6 and 12 May 2019.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Pablo Cuevas | 67 | 1 | ||
 Czech Republic | Jiří Veselý | 91 | 2 | |
| Lloyd Harris | 94 | 3 | ||
 Uzbekistan | Denis Istomin | 106 | 4 | |
 Brazil | Thiago Monteiro | 111 | 5 | |
| Yannick Maden | 114 | 6 | ||
 France | Grégoire Barrère | 117 | 7 | |
 Spain | Guillermo García López | 124 | 8 | |
 Canada | Peter Polansky | 125 | 9 | |
 Italy | Stefano Travaglia | 128 | 10 | |
| France | Antoine Hoang | 145 | 11 | |
| Italy | Gianluca Mager | 147 | 12 | |
| Marcos Giron | 154 | 13 | ||
| Rudolf Molleker | 157 | 14 | ||
| Italy | ||||
| Italy | Lorenzo Giustino | 161 | 16 |
The following players received wildcards into the singles main draw:
Antoine Cornut Chauvinc Hugo Gaston Matteo Martineau Thiago MonteiroThe following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Jonathan Kanar Jürgen MelzerSee main article: 2019 Open du Pays d'Aix – Singles.
Quentin Halys 7–5, 3–6, 6–2.See main article: 2019 Open du Pays d'Aix – Doubles.
Jürgen Melzer def. Frederik Nielsen / Tim Pütz 7–6(7–5), 6–2.