| Date: | 29 July – 4 August |
| Edition: | 34th (men) 5th (women) |
| Category: | ATP Challenger Tour ITF Women's Circuit |
| Location: | Segovia, Spain |
| Champms: |  Nicola Kuhn |
| Champws: | Arantxa Rus |
| Champmd: | Sander Arends / David Pel |
| Champwd: | Marina Bassols Ribera /  Feng Shuo |
| After Year: | 2021 |
The 2019 Open Castilla y León was a professional tennis tournament played on outdoor hard courts. It was the 34th edition, for men, and 5th edition, for women, of the tournament and part of the 2019 ATP Challenger Tour and the 2019 ITF Women's World Tennis Tour. It took place in El Espinar, Segovia, Spain, between 29 July – 4 August 2019.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Blaž Rola | 161 | 1 | ||
| Tallon Griekspoor | 191 | 2 | ||
 France | Constant Lestienne | 196 | 3 | |
 Italy | Andrea Arnaboldi | 218 | 4 | |
| Spain | Nicola Kuhn | 235 | 5 | |
| Italy | Matteo Viola | 243 | 6 | |
| Italy | Luca Vanni | 246 | 7 | |
| France | Kenny de Schepper | 273 | 8 | |
| Spain | Roberto Ortega Olmedo | 274 | 9 | |
 Russian Federation | Pavel Kotov | 287 | 10 | |
| Spain | Oriol Roca Batalla | 315 | 11 | |
| Scott Griekspoor | 328 | 12 | ||
| Italy | Andrea Vavassori | 330 | 13 | |
| France | Baptiste Crepatte | 332 | 14 | |
 Uzbekistan | Khumoyun Sultanov | 343 | 15 | |
 Bosnia and Herzegovina | Aldin Šetkić | 348 | 16 |
The following players received wildcards into the singles main draw:
Nicolás Álvarez Varona Íñigo Cervantes Miguel Damas Mario González Fernández
Digvijaypratap SinghThe following player received entry into the singles main draw using a protected ranking:
The following players received entry into the singles main draw using their ITF World Tennis Ranking:
The following players received entry from the qualifying draw:
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Arantxa Rus | 130 | 1 | ||
| Spain | Cristina Bucșa | 215 | 2 | |
| Elitsa Kostova | 227 | 3 | ||
| Spain | Nuria Párrizas Díaz | 269 | 4 | |
 Poland | Urszula Radwańska | 271 | 5 | |
| Spain | Olga Sáez Larra | 284 | 6 | |
| Spain | Eva Guerrero Álvarez | 298 | 7 | |
 Ukraine | Olga Ianchuk | 343 | 8 |
The following players received wildcards into the singles main draw:
Ángela Díez Plágaro Ángeles Moreno Barranquero Olga Parres Azcoitia Raquel Villán PereiraThe following players received entry into the singles main draw using their ITF World Tennis Ranking:
Alba Carrillo Marín Daria Mishina Júlia PayolaThe following players received entry from the qualifying draw:
Ainhoa Atucha Gómez Lucía Cortez Llorca
Julieta Lara Estable Feng Shuo Eugenia Ganga Almudena Sanz Llaneza FernándezSee main article: 2019 Open Castilla y León – Men's singles.
Nicola Kuhn def. Pavel Kotov 6–2, 7–6(7–4).See main article: 2019 Open Castilla y León – Men's doubles.
Orlando Luz / Felipe Meligeni Alves 6–4, 7–6(7–3). Marina Bassols Ribera / Feng Shuo def. 
Alexandra Bozovic / 
Shalimar Talbi, 7–5, 7–6(7–4)
