| Date: | 21–27 October (men) 28 October–3 November (women) |
| Edition: | 2nd (men) 4th (women) |
| Category: | ATP Challenger Tour ITF Women's Circuit |
| Surface: | Hard / Outdoors |
| Location: | Liuzhou, China |
| Champms: |  Alejandro Davidovich Fokina |
| Champmd: |  Mikhail Elgin /  Denis Istomin |
| Champws: |  Zhu Lin |
| Champwd: | Jiang Xinyu / Tang Qianhui |
| Before Name: | Liuzhou International Challenger |
The 2019 Liuzhou Open was a professional tennis tournament played on hard courts. It was the second edition of the tournament for men and fourth edition for women. It was the part of the 2019 ATP Challenger Tour and 2019 ITF Women's World Tennis Tour. It took place in Liuzhou, China between 21 October and 3 November 2019.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 India | Prajnesh Gunneswaran | 82 | 1 | |
| Spain | Alejandro Davidovich Fokina | 101 | 2 | |
| Jason Jung | 135 | 3 | ||
 Tunisia | Malek Jaziri | 148 | 4 | |
 Canada | Steven Diez | 156 | 5 | |
| Spain | Enrique López Pérez | 188 | 6 | |
 Serbia | Danilo Petrović | 195 | 7 | |
 United States | Christopher Eubanks | 203 | 8 | |
| Uzbekistan | Denis Istomin | 206 | 9 | |
 Egypt | Mohamed Safwat | 216 | 10 | |
| China | Bai Yan | 222 | 11 | |
| Frederico Ferreira Silva | 223 | 12 | ||
| Russian Federation | Roman Safiullin | 229 | 13 | |
| China | Li Zhe | 232 | 14 | |
| Wu Tung-lin | 236 | 15 | ||
 Korea, Republic of | Lee Duck-hee | 248 | 16 |
The following players received wildcards into the singles main draw:
Li Yuanfeng Mo Yecong Wang Aoran Wu Hao Xia ZihaoThe following player received entry into the singles main draw using a protected ranking:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| China | Zhu Lin | 95 | 1 | |
| Serbia | Nina Stojanović | 101 | 2 | |
| China | Wang Xinyu | 142 | 3 | |
 Georgia | Mariam Bolkvadze | 158 | 4 | |
| Korea, Republic of | Han Na-lae | 159 | 5 | |
| Russian Federation | Valeria Savinykh | 162 | 6 | |
| China | ||||
| Serbia | Natalija Kostić | 176 | 8 |
The following players received wildcards into the singles main draw:
The following player received special exempts into the singles main draw:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
See main article: 2019 Liuzhou Open – Men's singles.
Alejandro Davidovich Fokina def. Denis Istomin 6–3, 5–7, 7–6(7–5).See main article: 2019 Liuzhou Open – Women's singles.
Zhu Lin def. 
Arina Rodionova, 2–6, 6–0, 6–1See main article: 2019 Liuzhou Open – Men's doubles.
Mikhail Elgin / Denis Istomin def. Nam Ji-sung / Song Min-kyu 3–6, 6–4, [10–6].See main article: 2019 Liuzhou Open – Women's doubles.
Jiang Xinyu / Tang Qianhui def. Ankita Raina / Rosalie van der Hoek, 6–4, 6–4
