| Champ: |  Andrey Rublev |
| Runner: |  Adrian Mannarino |
| Score: | 6–4, 6–0 |
| Draw: | 28 (4 / 3) |
| Seeds: | 8 |
| Before Name: | Kremlin Cup – Men's singles |
| After Name: | Kremlin Cup – Men's singles |
| After Year: | 2021 |
See main article: article and 2019 Kremlin Cup.
Karen Khachanov was the defending champion,[1] but lost in the quarterfinals to Andreas Seppi.
Andrey Rublev won the title, defeating Adrian Mannarino in the final, 6–4, 6–0.
The top four seeds received a bye into the second round.
