The 2019 Internazionali Femminili di Palermo was a professional women's tennis tournament played on outdoor clay courts at the Country Time Club. It was the 27th edition of the tournament which was part of the 2019 WTA Tour. It took place in Palermo, Italy between 22 and 28 July 2019.[1] The tournament made a return to the WTA Tour after a five-year absence (2014–2018).
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Kiki Bertens | 5 | 1 | ||
 France | Alizé Cornet | 48 | 2 | |
 Slovakia | Viktória Kužmová | 54 | 3 | |
| Tamara Zidanšek | 57 | 4 | ||
| France | Pauline Parmentier | 75 | 5 | |
| Laura Siegemund | 77 | 6 | ||
| Sara Sorribes Tormo | 87 | 7 | ||
| Jil Teichmann | 90 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry using a protected ranking into the main draw:
The following player received entry as a special exempt into the main draw:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Liudmila Samsonova
Aliona Bolsova → replaced by Antonia Lottner
Martina Di Giuseppe → replaced by 
Fanny Stollár
Irina-Camelia Begu Lara Arruabarrena
Mandy Minella → replaced by Georgina García Pérez
Karolína Muchová → replaced by Paula Badosa Anna Karolína Schmiedlová → replaced by Stefanie Vögele
Zhang Shuai → replaced by 
Ekaterine Gorgodze| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
 Sweden | Cornelia Lister | Czech Republic | Renata Voráčová | 170 | 1 | |
| Spain | Georgina García Pérez | Hungary | Fanny Stollár | 204 | 2 | |
 Australia | Daria Gavrilova | China | Peng Shuai | 239 | 3 | |
| Italy | Giorgia Marchetti |  Brazil | Laura Pigossi | 316 | 4 |
The following pairs received wildcards into the doubles main draw:
Martina Di Giuseppe (viral illness)See main article: 2019 Internazionali Femminili di Palermo – Singles.
See main article: 2019 Internazionali Femminili di Palermo – Doubles.
Cornelia Lister / Renata Voráčová defeated Ekaterine Gorgodze / Arantxa Rus, 7–6(7–2), 6–2