The 2019 Internationaux de Tennis de Blois was a professional tennis tournament played on clay courts. It was the seventh edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Blois, France between 17 and 23 June 2019.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Pedro Sousa | 124 | 1 | ||
 Spain | Pedro Martínez | 126 | 2 | |
 Italy | Lorenzo Giustino | 144 | 3 | |
 Belgium | Kimmer Coppejans | 166 | 4 | |
 Argentina | Carlos Berlocq | 177 | 5 | |
 Colombia | Daniel Elahi Galán | 186 | 6 | |
 France | ||||
| Argentina | Federico Coria | 201 | 8 | |
| Argentina | Facundo Argüello | 202 | 9 | |
| France | Constant Lestienne | 206 | 10 | |
| France | ||||
| Argentina | Pedro Cachin | 236 | 12 | |
| Spain | Bernabé Zapata Miralles | 241 | 13 | |
 Canada | Steven Diez | 243 | 14 | |
 Japan | Kaichi Uchida | 245 | 15 | |
| France | Johan Tatlot | 253 | 16 | |
| France | Tristan Lamasine | 254 | 17 |
The following players received wildcards into the singles main draw:
Samuel Brosset Maxime Hamou Matteo Martineau Enzo WallartThe following players received entry into the singles main draw using their ITF World Tennis Ranking:
The following player received entry into the singles main draw using a protected ranking:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Youlian IakovlevSee main article: 2019 Internationaux de Tennis de Blois – Singles.
Kimmer Coppejans 4–6, 6–3, 7–6(7–4).See main article: 2019 Internationaux de Tennis de Blois – Doubles.
Corentin Denolly / Alexandre Müller def. 
Sergio Galdós / 
Andreas Siljeström 7–5, 6–7(5–7), [10–6].