| Date: | 4–10 November 2019 |
| Edition: | 11th |
| Surface: | Hard |
| Location: | Las Vegas, United States |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $60,000 |
| Champs: |  Mayo Hibi |
| Champd: |  Olga Govortsova /  Mandy Minella |
| Before Name: | Red Rock Pro Open |
| After Year: | 2021 |
The 2019 Henderson Tennis Open was a professional tennis tournament played on outdoor hard courts. It was the eleventh edition of the tournament which was part of the 2019 ITF Women's World Tennis Tour. It took place in Las Vegas, United States between 4 and 10 November 2019.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Belgium | Kirsten Flipkens | 99 | 1 | |
 Romania | Patricia Maria Țig | 115 | 2 | |
 Ukraine | Katarina Zavatska | 117 | 3 | |
| Stefanie Vögele | 123 | 4 | ||
| Varvara Lepchenko | 135 | 5 | ||
| Ann Li | 147 | 6 | ||
| Sachia Vickery | 160 | 7 | ||
| Caroline Dolehide | 166 | 8 |
The following players received wildcards into the singles main draw:
The following player received a special exempt into the singles main draw:
The following players received entry from the qualifying draw:
Vladica Babić
Charlotte Chavatipon Quinn Gleason
María Gutiérrez Carrasco Alycia Parks Natasha Subhash
Marcela ZacaríasThe following player received entry as a lucky loser:
See main article: 2019 Henderson Tennis Open – Singles.
Mayo Hibi def. Anhelina Kalinina, 6–2, 5–7, 6–2See main article: 2019 Henderson Tennis Open – Doubles.
Olga Govortsova / Mandy Minella def. Sophie Chang / Alexandra Mueller, 6–3, 6–4