The 2019 Guzzini Challenger was a professional tennis tournament played on hard courts. It was the seventeenth edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Recanati, Italy between 1 and 7 July 2019.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Matthias Bachinger | 121 | 1 | ||
 Russian Federation | Evgeny Donskoy | 129 | 2 | |
 Italy | Lorenzo Giustino | 134 | 3 | |
 Ukraine | Sergiy Stakhovsky | 139 | 4 | |
 Belarus | Ilya Ivashka | 140 | 5 | |
 Slovakia | Lukáš Lacko | 144 | 6 | |
 Spain | Adrián Menéndez Maceiras | 148 | 7 | |
| Italy | Filippo Baldi | 151 | 8 | |
 India | Ramkumar Ramanathan | 154 | 9 | |
| Belarus | Egor Gerasimov | 170 | 10 | |
| Italy | Stefano Napolitano | 179 | 11 | |
 Ecuador | Emilio Gómez | 185 | 12 | |
| Viktor Galović | 199 | 13 | ||
 Bosnia and Herzegovina | Mirza Bašić | 203 | 14 | |
| Mats Moraing | 208 | 15 | ||
| Spain | Enrique López Pérez | 211 | 16 |
The following players received wildcards into the singles main draw:
Enrico Dalla Valle Giovanni Fonio Emiliano Maggioli Lorenzo MusettiThe following player received entry into the singles main draw as an alternate:
The following players received entry into the singles main draw using their ITF World Tennis Ranking:
The following players received entry from the qualifying draw:
Nikola Ćaćić Samuele RamazzottiSee main article: 2019 Guzzini Challenger – Singles.
Egor Gerasimov def. Roberto Marcora 6–2, 7–5.See main article: 2019 Guzzini Challenger – Doubles.
Ramkumar Ramanathan def. Andrea Vavassori / David Vega Hernández 6–2, 6–4.
