| Date: | 3–9 June (women) 17–23 June (men) |
| Edition: | 20th (men) 9th (women) |
| Surface: | Hard |
| Location: | Fergana, Uzbekistan |
| Prize Money: | $54,160 (men) $25,000 (women) |
| Champms: |  Emil Ruusuvuori |
| Champws: |  Kamilla Rakhimova |
| Champmd: |  Evan King / Hunter Reese |
| Champwd: |  Nigina Abduraimova /  Berfu Cengiz |
The 2019 Fergana Challenger was a professional tennis tournament played on hard courts. It was the 20th edition of the tournament for men which was part of the 2019 ATP Challenger Tour, and the ninth edition of the event for women on the 2019 ITF Women's World Tennis Tour. It took place in Fergana, Uzbekistan, between 3–9 June (women) and 17–23 June (men).
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Serbia | Peđa Krstin | 209 | 1 | |
 France | Gleb Sakharov | 264 | 2 | |
| Marc-Andrea Hüsler | 270 | 3 | ||
| Turkey | Cem İlkel | 275 | 4 | |
 India | Sasikumar Mukund | 282 | 5 | |
| Marcelo Tomás Barrios Vera | 284 | 6 | ||
| Russian Federation | Pavel Kotov | 286 | 7 | |
| Yang Tsung-hua | 296 | 8 | ||
 Kazakhstan | Denis Yevseyev | 306 | 9 | |
 Australia | Aleksandar Vukic | 310 | 10 | |
| United States | Evan King | 316 | 11 | |
 Dominican Republic | Roberto Cid Subervi | 329 | 12 | |
 Bosnia and Herzegovina | Aldin Šetkić | 331 | 13 | |
| France | Baptiste Crepatte | 340 | 14 | |
| Alejandro Tabilo | 341 | 15 | ||
 China | Wu Di | 348 | 16 |
The following players received wildcards into the singles main draw:
Olimjon Nabiev Saida'Lo Saidkarimov Shonigmatjon Shofayziyev Timur Sottimov Ibrokhimjon UrinovThe following players received entry into the singles main draw using their ITF World Tennis Ranking:
The following players received entry into the singles main draw as alternates:
Anton Chekhov Sergey Fomin Vijay Sundar PrashanthThe following players received entry from the qualifying draw:
Timur Khabibulin Alexey Zakharov| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Uzbekistan | Sabina Sharipova | 169 | 1 | |
| Russian Federation | Sofya Lansere | 312 | 2 | |
| Turkey | Berfu Cengiz | 341 | 3 | |
| Uzbekistan | Nigina Abduraimova | 351 | 4 | |
| Russian Federation | Ekaterina Yashina | 379 | 5 | |
| Russian Federation | Kamilla Rakhimova | 422 | 6 | |
| Russian Federation | Polina Monova | 427 | 7 | |
| Kazakhstan | Gozal Ainitdinova | 481 | 8 |
The following players received wildcards into the singles main draw:
Yekaterina Dmitrichenko Milana Maslenkova Setora Normurodova Sarvinoz SaidhujaevaThe following players received entry into the singles main draw using their ITF World Tennis Ranking:
Daria Kruzhkova
Sadafmoh Tolibova Valeriya Yushchenko
Marianna Zakarlyuk Anastasia ZakharovaThe following players received entry from the qualifying draw:
Isabella Bozicevic Dariya Detkovskaya Arina Folts Shakhnoza Khatamova Ksenia Kolesnikova Margarita Lazareva Ekaterina Nikiforova Sevil YuldashevaSee main article: 2019 Fergana Challenger – Men's singles.
Emil Ruusuvuori def. Roberto Cid Subervi 6–3, 6–2. Kamilla Rakhimova def. Valeriya Yushchenko, 6–1, 7–5See main article: 2019 Fergana Challenger – Men's doubles.
Evan King / Hunter Reese def. Nikola Čačić / Yang Tsung-hua 6–3, 5–7, [10–4]. Nigina Abduraimova / Berfu Cengiz def. Isabella Bozicevic / Ksenia Laskutova, 4–6, 6–1, [10–3]