The women's 4 × 400 metres relay event at the 2019 European Athletics Indoor Championships was held on 3 March 2019 at 20:40 (final) local time.
| World record | 3:23.37 | Glasgow, United Kingdom | 28 January 2006 | ||
| European record | |||||
| Championship record | 3:27.56 | Gothenburg, Sweden | 3 March 2013 | ||
| World Leading | Texas A&M University | 3:29.15 | Fayetteville, United States | 23 February 2019 | |
| European Leading | 3:33.76 | Istanbul, Turkey | 16 February 2019 |
| Rank | Nationality | Athlete | Time | Notes | |
|---|---|---|---|---|---|
| Anna Kiełbasińska Iga Baumgart-Witan Małgorzata Hołub-Kowalik Justyna Święty-Ersetic | 3:28.77 | WL | |||
| Laviai Nielsen Zoey Clark Amber Anning Eilidh Doyle | 3:29.55 | ||||
| Raphaela Boaheng Lukudo Ayomide Folorunso Chiara Bazzoni Marta Milani | 3:31.90 | ||||
| 4 | Déborah Sananes Amandine Brossier Kalyl Amaro Agnès Raharolahy | 3:32.12 | |||
| 5 | Cynthia Bolingo Mbongo Hanne Claes Margo Van Puyvelde Camille Laus | 3:32.46 | NR | ||
| 6 | Cornelia Halbheer Léa Sprunger Fanette Humair Yasmin Giger | 3:33.72 | NR |