| Champ: |  Karolína Plíšková |
| Runner: | Angelique Kerber |
| Score: | 6–1, 6–4 |
| After Year: | 2021 |
See main article: article and 2019 Eastbourne International.
Caroline Wozniacki was the defending champion, but lost in the third round to Aryna Sabalenka in a rematch of the previous year's final.
Karolína Plíšková reached her third Eastbourne final in four years, and claimed her second title, defeating Angelique Kerber in the final 6–1, 6–4.
The top eight seeds received a bye into the second round.