| Champ: | Belinda Bencic |
| Runner: |  Petra Kvitová |
| Score: | 6–3, 1–6, 6–2 |
| Draw: | 56 |
| Seeds: | 16 |
See main article: 2019 Dubai Tennis Championships.
Belinda Bencic defeated Petra Kvitová in the final, 6–3, 1–6, 6–2 to win the women's singles tennis title at the 2019 Dubai Tennis Championships. She saved six match points en route to the title, in the third round against Aryna Sabalenka. For the second time in her career, Bencic defeated four consecutive top-ten players en route to a Premier 5 title. This was her first WTA singles title since winning the Premier 5 Rogers Cup title in 2015, and lifted her back inside the top 25 in rankings for the first time in over two and a half years.
Elina Svitolina was the two-time defending champion, but lost in the semifinals to Bencic.[1]
The top eight seeds received a bye into the second round.