| Mode: | Women's Basketball |
| Year: | 2019–20 |
| Prev Year: | 2018–19 |
| Next Year: | 2020–21 |
| Team: | Southern Miss Lady Eagles |
| Conference: | Conference USA |
| Short Conf: | C-USA |
| Record: | 15–15 |
| Conf Record: | 7–11 |
| Hc Year: | 16th |
| Asst Coach1: | Jack Trosper |
| Asst Coach2: | Patosha Jeffery |
| Asst Coach3: | Stephanie Stoglin-Reed |
The 2019–20 Southern Miss Lady Eagles basketball team represented the University of Southern Mississippi during the 2019–20 NCAA Division I women's basketball season. The Lady Eagles, led by sixteenth-year head coach Joye Lee-McNelis, played their home games at Reed Green Coliseum and were members of Conference USA (C-USA).
They finished the season 15–15, 7–11 in C-USA play, to finish in a tie for ninth place. They lost in the first round of the C-USA women's tournament to Marshall. The day following their loss, the rest of the games for the postseason tournament were cancelled due to COVID-19 concerns.[1]
|-!colspan=9 style=| Exhibition|-!colspan=9 style=| Non-conference regular season|-!colspan=9 style=| C-USA regular season|-!colspan=9 style=| C-USA tournamentSource:[2]