The 2018 U.S. Men's Clay Court Championships (also known as the Fayez Sarofim & Co. U.S. Men's Clay Court Championships for sponsorship purposes) was a tennis tournament played on outdoor clay courts. It was the 117th edition of the U.S. Men's Clay Court Championships, and an ATP World Tour 250 event on the 2018 ATP World Tour. It took place at River Oaks Country Club in Houston, Texas, United States, from April 9 through April 15, 2018.
See main article: 2018 U.S. Men's Clay Court Championships – Singles.
Steve Johnson defeated Tennys Sandgren, 7–6(7–2), 2–6, 6–4[1]See main article: 2018 U.S. Men's Clay Court Championships – Doubles.
Max Mirnyi / 
Philipp Oswald defeated Andre Begemann / Antonio Šančić, 6–7(2–7), 6–4, [11–9]| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| United States | John Isner | 9 | 1 | |
| United States | Sam Querrey | 14 | 2 | |
| United States | Jack Sock | 16 | 3 | |
 Australia | Nick Kyrgios | 24 | 4 | |
 Spain | Fernando Verdasco | 36 | 5 | |
| United States | Steve Johnson | 52 | 6 | |
| United States | Ryan Harrison | 54 | 7 | |
| United States | Tennys Sandgren | 56 | 8 |
The following players received wildcards into the main draw:
The following players received entry via the qualifying draw:
Jérémy Chardy → replaced by 
Taro Daniel
Chung Hyeon → replaced by Bjorn Fratangelo
Lukáš Lacko → replaced by Tim Smyczek Feliciano López → replaced by Henri Laaksonen John Millman → replaced by Ernesto Escobedo| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| United States | Bob Bryan | United States | Mike Bryan | 18 | 1 | |
| United States | Ryan Harrison | Japan | Ben McLachlan | 46 | 2 | |
| Julio Peralta |  Argentina | Horacio Zeballos | 59 | 3 | ||
 Mexico | Santiago González | United States | Donald Young | 86 | 4 |
The following pairs received wildcards into the doubles main draw:
