| Date: | 23–29 April |
| Edition: | 16th |
| Draw: | 32S / 16D |
| Surface: | Hard |
| Location: | León, Mexico |
| Champs: |  Christopher Eubanks |
| Champd: |  Gonzalo Escobar /  Manuel Sánchez |
The 2018 Torneo Internacional Challenger León was a professional tennis tournament played on hard courts. It was the sixteenth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in León, Mexico between 23 and 29 April 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Spain | Adrián Menéndez Maceiras | 156 | 1 | |
| Mats Moraing | 158 | 2 | ||
| Dennis Novikov | 167 | 3 | ||
 Dominican Republic | Víctor Estrella Burgos | 171 | 4 | |
| Kevin King | 172 | 5 | ||
| Darian King | 179 | 6 | ||
 Canada | Filip Peliwo | 180 | 7 | |
| Marcelo Arévalo | 181 | 8 |
The following players received wildcards into the singles main draw:
Tigre Hank Luis Patiño José Antonio Rodríguez Rodríguez Manuel SánchezThe following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
See main article: 2018 Torneo Internacional Challenger León – Singles.
Christopher Eubanks def. 
John-Patrick Smith 6–4, 3–6, 7–6(7–4).See main article: 2018 Torneo Internacional Challenger León – Doubles.
Gonzalo Escobar / Manuel Sánchez def. Bradley Mousley / John-Patrick Smith 6–4, 6–4.
