The 2018 Savannah Challenger was a professional tennis tournament played on clay courts. It was the tenth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Savannah, Georgia, United States between April 30 and May 6, 2018.
| Country | Player | Rank | Seed | |
|---|---|---|---|---|
| 120 | 1 | |||
 Canada | Peter Polansky | 124 | 2 | |
| Donald Young | 130 | 3 | ||
| 135 | 4 | |||
| Michael Mmoh | 144 | 5 | ||
| Blaž Rola | 170 | 6 | ||
 Bolivia, Plurination;al State of | Hugo Dellien | 172 | 7 | |
| Evan King | 185 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as a special exempt:
The following players received entry from the qualifying draw:
Federico Coria
Karue Sell João Pedro SorgiSee main article: 2018 Savannah Challenger – Singles.
Hugo Dellien def. 
Christian Harrison 6–1, 1–6, 6–4.See main article: 2018 Savannah Challenger – Doubles.
Luke Bambridge / 
Akira Santillan def. 
Enrique López Pérez / 
Jeevan Nedunchezhiyan 6–2, 6–2.