See main article: 2018 Rio Open. Pablo Carreño Busta and Pablo Cuevas were the defending champions, but withdrew before the tournament began.
David Marrero and Fernando Verdasco won the title, defeating Nikola Mektić and Alexander Peya in the final, 5–7, 7–5, [10–8]. Marrero and Verdasco were the first lucky loser team to win an ATP World Tour doubles title since 2014.[1]