| Date: | 5–11 November |
| Edition: | 10th |
| Category: | ITF Women's Circuit |
| Location: | Las Vegas, United States |
| Surface: | Hard |
| Prize Money: | $80,000 |
| Champs: | Belinda Bencic |
| Champd: |  Asia Muhammad / Maria Sanchez |
| After Name: | Henderson Tennis Open |
The 2018 Red Rock Pro Open was a professional tennis tournament played on outdoor hard courts. It was the tenth edition of the tournament and was part of the 2018 ITF Women's Circuit. It took place in Las Vegas, United States, on 5–11 November 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Belinda Bencic | 39 | 1 | ||
 United Kingdom | Heather Watson | 99 | 2 | |
 Hungary | Fanny Stollár | 128 | 3 | |
| United States | Varvara Lepchenko | 130 | 4 | |
 Russian Federation | Sofya Zhuk | 133 | 5 | |
 Czech Republic | Marie Bouzková | 142 | 6 | |
| Verónica Cepede Royg | 145 | 7 | ||
| United States | Nicole Gibbs | 146 | 8 |
The following players received a wildcard into the singles main draw:
The following player received entry using a protected ranking:
The following players received entry from the qualifying draw:
See main article: 2018 Red Rock Pro Open – Singles.
Nicole Gibbs, 7–5, 6–1See main article: 2018 Red Rock Pro Open – Doubles.
Asia Muhammad / Maria Sanchez def. Sophie Chang / Alexandra Mueller, 6–3, 6–4
