| Date: | 19–25 March |
| Edition: | 1st |
| Surface: | Hard (indoor) |
| Location: | Lille, France |
| Champs: |  Grégoire Barrère |
| Champd: | Hugo Nys / Tim Pütz |
The 2018 Play In Challenger was a professional tennis tournament played on indoor hard courts. It was the first edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Lille, France, between 19 and 25 March 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| France | Nicolas Mahut | 101 | 1 | |
| France | Quentin Halys | 121 | 2 | |
| Yannick Maden | 136 | 3 | ||
| Oscar Otte | 137 | 4 | ||
| France | Corentin Moutet | 138 | 5 | |
| France | Stéphane Robert | 159 | 6 | |
| Matthias Bachinger | 171 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
See main article: 2018 Play In Challenger – Singles.
Grégoire Barrère def. Tobias Kamke 6–1, 6–4.See main article: 2018 Play In Challenger – Doubles.
Hugo Nys / Tim Pütz def. 
Jeevan Nedunchezhiyan / Purav Raja 7–6(7–3), 1–6, [10–7].
