| Year: | 2018 |
| Team: | Penn Quakers |
| Sport: | football |
| Conference: | Ivy League |
| Short Conf: | Ivy |
| Record: | 6–4 |
| Conf Record: | 3–4 |
| Head Coach: | Ray Priore |
| Hc Year: | 4th |
| Off Coach: | John Reagan |
| Oc Year: | 4th |
| Def Coach: | Bob Benson |
| Dc Year: | 4th |
| Stadium: | Franklin Field |
The 2018 Penn Quakers football team represented the University of Pennsylvania during the 2018 NCAA Division I FCS football season. They were led by fourth-year head coach Ray Priore and played their home games at Franklin Field. They were a member of the Ivy League. They finished the season 6–4 overall 3–3 in Ivy League play to place in a three-way tie for fourth. Penn averaged 7,767 fans per game.
| Buck Buchanan Award[1] | Nick Miller | LB | SR |
See also: 2018 Bucknell Bison football team.
See also: 2018 Lehigh Mountain Hawks football team.
See also: 2018 Dartmouth Big Green football team.
See also: 2018 Sacred Heart Pioneers football team.
See also: 2018 Columbia Lions football team.
See also: 2018 Yale Bulldogs football team.
See also: 2018 Brown Bears football team.
See also: 2018 Cornell Big Red football team and Cornell–Penn football rivalry.
See also: 2018 Harvard Crimson football team and Harvard–Penn football rivalry.
See also: 2018 Princeton Tigers football team and Penn–Princeton football rivalry.