| Date: | November 12–18 |
| Edition: | 1st |
| Draw: | 32S / 16D |
| Surface: | Hard, outdoor |
| Prize Money: | $150,000+H (ATP) $150,000 (WTA) |
| Category: | ATP Challenger Tour WTA 125K series |
| Location: | Houston, United States |
| Venue: | George R. Brown Tennis Center |
| Champms: |  Bradley Klahn |
| Champmd: | Austin Krajicek / Nicholas Monroe |
| Champws: |  Peng Shuai |
| Champwd: | Maegan Manasse / Jessica Pegula |
The 2018 Oracle Challenger Series – Houston was a professional tennis tournament played on outdoor hard courts. This tournament was part of the 2018 ATP Challenger Tour and the 2018 WTA 125K series.[1] The first edition took place at the George R. Brown Tennis Center from November 12 to 18, 2018 in Houston, United States.[2]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Tennys Sandgren | 61 | 1 | ||
| Bradley Klahn | 95 | 2 | ||
| Ivo Karlović | 102 | 3 | ||
 Italy | Paolo Lorenzi | 115 | 4 | |
| Jason Jung | 128 | 5 | ||
| Bjorn Fratangelo | 131 | 6 | ||
| Tim Smyczek | 140 | 7 | ||
| Dominik Köpfer | 177 | 8 |
The following players received wildcards into the singles main draw:
Tom Fawcett Sumit Sarkar Ronnie Schneider Roy SmithThe following players received entry from the qualifying draw:
Harrison Adams
Alexis Galarneau Michael Redlicki| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Belinda Bencic | 37 | 1 | ||
 Romania | ||||
 United Kingdom | Heather Watson | 101 | 3 | |
| Jessica Pegula | 125 | 4 | ||
 Hungary | Fanny Stollár | 127 | 5 | |
| Varvara Lepchenko | 129 | 6 | ||
 Russian Federation | Sofya Zhuk | 133 | 7 | |
 Czech Republic | Marie Bouzková | 142 | 8 | |
| Nicole Gibbs | 147 | 9 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following players received entry into the main draw as lucky losers:
Kristie Ahn → replaced by 
Beatriz Haddad Maia Eugenie Bouchard → replaced by Jacqueline Cako
Deniz Khazaniuk Kayla Day → replaced by Réka Luca Jani Julia Glushko → replaced by Naomi Broady Claire Liu → replaced by Louisa Chirico Christina McHale → replaced by Deborah Chiesa Monica Niculescu → replaced by Katherine Sebov Dalma Gálfi (back injury)| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| United Kingdom | Naomi Broady | Sabrina Santamaria | 143 | 1 | ||
| Asia Muhammad | Maria Sanchez | 151 | 2 | |||
| Desirae Krawczyk |  Mexico | Giuliana Olmos | 152 | 3 | ||
| Alexa Guarachi |  New Zealand | Erin Routliffe | 184 | 4 |
The following pair received a wildcard into the doubles main draw:
Anna Bowtell / 
Victoria SmirnovaSee main article: article and 2018 Oracle Challenger Series – Houston – Men's singles.
Bradley Klahn def. Roy Smith 7–6(7–4), 7–6(7–4).See main article: article and 2018 Oracle Challenger Series – Houston – Women's singles.
Peng Shuai def. Lauren Davis 1–6, 7–5, 6–4See main article: article and 2018 Oracle Challenger Series – Houston – Men's doubles.
Austin Krajicek / Nicholas Monroe def. Marcelo Arévalo / James Cerretani 4–6, 7–6(7–3), [10–5].See main article: article and 2018 Oracle Challenger Series – Houston – Women's doubles.
Maegan Manasse / Jessica Pegula def. Desirae Krawczyk / Giuliana Olmos, 1–6, 6–4, [10–8]
