| Date: | 24–30 September |
| Edition: | 14th |
| Draw: | 32S / 16D |
| Surface: | Hard |
| Location: | Orléans, France |
| Champs: | Aljaž Bedene |
| Champd: |  Luke Bambridge / Jonny O'Mara |
The 2018 Open d'Orléans was a professional tennis tournament played on indoor hard courts. It was the fourteenth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Orléans, France between 24 and 30 September 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 France | ||||
| Aljaž Bedene | 76 | 2 | ||
 Spain | Jaume Munar | 82 | 3 | |
 Italy | Lorenzo Sonego | 90 | 4 | |
| France | Corentin Moutet | 105 | 5 | |
| France | Ugo Humbert | 108 | 6 | |
| Yannick Maden | 120 | 7 | ||
 Estonia | Jürgen Zopp | 122 | 8 |
The following players received wildcards into the singles main draw:
Antoine Cornut Chauvinc Antoine Hoang
Sergiy StakhovskyThe following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Maxime JanvierSee main article: 2018 Open d'Orléans – Singles.
Antoine Hoang 4–6, 6–1, 7–6(8–6).See main article: 2018 Open d'Orléans – Doubles.
Luke Bambridge / Jonny O'Mara def. Yannick Maden / 
Tristan-Samuel Weissborn 6–2, 6–4.