| Date: | 13–19 August |
| Edition: | 13th (ATP) 16th (ITF) |
| Category: | ATP Challenger Tour ITF Women's Circuit |
| Location: | Vancouver, British Columbia, Canada |
| Prize Money: | $100,000 (ATP) $100,000 (ITF) |
| Champms: |  Dan Evans |
| Champws: |  Misaki Doi |
| Champmd: | Luke Bambridge / Neal Skupski |
| Champwd: |  Desirae Krawczyk /  Giuliana Olmos |
| Main Name: | Vancouver Open |
The 2018 Odlum Brown Vancouver Open was a professional tennis tournament played on outdoor hard courts. It was the thirteenth (ATP) and sixteenth (ITF) editions of the tournament and was part of the 2018 ATP Challenger Tour and the 2018 ITF Women's Circuit. It took place in Vancouver, British Columbia, Canada, on 13–19 August 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Canada | Vasek Pospisil | 94 | 1 | |
 Australia | Jordan Thompson | 100 | 2 | |
 Italy | Thomas Fabbiano | 105 | 3 | |
| Australia | Jason Kubler | 106 | 4 | |
 Luxembourg | Gilles Müller | 114 | 5 | |
| Canada | Peter Polansky | 121 | 6 | |
 Belarus | Ilya Ivashka | 125 | 7 | |
 Belgium | Ruben Bemelmans | 130 | 8 |
The following players received a wildcard into the singles main draw:
The following players received entry into the singles main draw using protected rankings:
The following players received entry into the singles main draw as special exempts:
The following players received entry from the qualifying draw:
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Ukraine | Kateryna Kozlova | 89 | 1 | |
| Belgium | Yanina Wickmayer | 94 | 2 | |
 Russian Federation | Ekaterina Alexandrova | 99 | 3 | |
 Tunisia | Ons Jabeur | 112 | 4 | |
| United Kingdom | Katie Boulter | 114 | 5 | |
| Arantxa Rus | 116 | 7 | ||
 Brazil | Beatriz Haddad Maia | 118 | 8 |
The following players received a wildcard into the singles main draw:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
See main article: 2018 Odlum Brown Vancouver Open – Men's singles.
Dan Evans def. Jason Kubler 4–6, 7–5, 7–6(7–3)See main article: 2018 Odlum Brown Vancouver Open – Women's singles.
Misaki Doi def. Heather Watson 6–7(4–7), 6–1, 6–4See main article: 2018 Odlum Brown Vancouver Open – Men's doubles.
Luke Bambridge / Neal Skupski def. Marc Polmans / Max Purcell 4–6, 6–3, [10–6].See main article: 2018 Odlum Brown Vancouver Open – Women's doubles.
Desirae Krawczyk / Giuliana Olmos def. Kateryna Kozlova / Arantxa Rus, 6–2, 7–5
