| Date: | 13–19 August |
| Edition: | 6th |
| Draw: | 32S/16D |
| Surface: | Clay |
| Location: | Meerbusch, Germany |
| Champs: |  Filip Horanský |
| Champd: |  David Pérez Sanz / Mark Vervoort |
| Before Name: | Bucher Reisen Tennis Grand Prix |
The 2018 Meerbusch Challenger was a professional tennis tournament played on clay courts. It was the sixth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Meerbusch, Germany, between 13 and 19 August 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Spain | Sergio Gutiérrez Ferrol | 158 | 1 | |
| Pedro Sousa | 166 | 2 | ||
 Russian Federation | ||||
 Austria | Sebastian Ofner | 210 | 4 | |
| Russian Federation | Ivan Nedelko | 238 | 5 | |
| Slovakia | Filip Horanský | 245 | 6 | |
 Belgium | Arthur De Greef | 247 | 7 | |
| Rudolf Molleker | 251 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw using a protected ranking:
The following player received entry into the singles main draw as a special exempt:
The following players received entry from the qualifying draw:
Zizou Bergs Nicola KuhnThe following player received entry as a lucky loser:
See main article: 2018 Meerbusch Challenger – Singles.
Filip Horanský def. Jan Choinski 6–7(7–9), 6–3, 6–3.See main article: 2018 Meerbusch Challenger – Doubles.
David Pérez Sanz / Mark Vervoort def. 
Grzegorz Panfil / 
Volodymyr Uzhylovskyi 3–6, 6–4, [10–7].
