| Date: | 17–23 September |
| Edition: | 23rd |
| Category: | ITF Women's Circuit |
| Location: | Saint-Malo, France |
| Prize Money: | $60,000+H |
| Champs: |  Liudmila Samsonova |
| Champd: |  Cristina Bucșa /  María Fernanda Herazo |
| Before Name: | L'Open Emeraude Solaire de Saint-Malo |
The 2018 L'Open 35 de Saint-Malo was a professional tennis tournament played on outdoor clay courts. It was the twenty-third edition of the tournament and was part of the 2018 ITF Women's Circuit. It took place in Saint-Malo, France, on 17–23 September 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Ukraine | Anhelina Kalinina | 113 | 2 | |
 Belgium | Ysaline Bonaventure | 119 | 3 | |
 Uzbekistan | ||||
| Laura Siegemund | 146 | 5 | ||
 Romania | Irina Bara | 150 | 6 | |
| Russian Federation | Irina Khromacheva | 154 | 7 | |
| Verónica Cepede Royg | 157 | 8 | ||
 Liechtenstein | Kathinka von Deichmann | 159 | 9 | |
 Czech Republic | Tereza Smitková | 160 | 10 |
The following players received a wildcard into the singles main draw:
Clara Burel Harmony Tan Lucie WargnierThe following players received entry from the qualifying draw:
The following players received entry as lucky losers:
See main article: 2018 L'Open 35 de Saint-Malo – Singles.
Liudmila Samsonova def. Katarina Zavatska, 6–0, 6–2See main article: 2018 L'Open 35 de Saint-Malo – Doubles.
Cristina Bucșa / María Fernanda Herazo def. Alexandra Cadanțu / Diāna Marcinkēviča, 4–6, 6–1, [10–8]