| Champ: |  Daria Kasatkina |
| Runner: |  Ons Jabeur |
| Score: | 2–6, 7–6(7–3), 6–4 |
See main article: article and 2018 Kremlin Cup. Julia Görges was the defending champion, but chose to compete in Luxembourg instead.
Daria Kasatkina won the title, defeating Ons Jabeur in the final, 2–6, 7–6(7–3), 6–4.
Jabeur became the first player representing Tunisia to reach a WTA final. With her win over Jabeur, Kasatkina broke inside the top 10 world ranking for the first time in her career, and qualified for the 2018 WTA Finals as the first alternate, replacing Aryna Sabalenka.[1]
The top four seeds received a bye into the second round.