| Champ: |  Steve Johnson |
| Runner: |  Ramkumar Ramanathan |
| Score: | 7–5, 3–6, 6–2 |
| Draw: | 28 (4 / 3) |
| Seeds: | 8 |
| Type: | singles doubles |
| After Name: | Hall of Fame Open |
See main article: article and 2018 Hall of Fame Tennis Championships.
John Isner was the defending champion, but withdrew before the tournament began.
Steve Johnson won his fourth career ATP World Tour title, defeating Ramkumar Ramanathan in the final, 7–5, 3–6, 6–2. Ramanathan was making his first appearance in a World Tour final.
The top four seeds receive a bye into the second round.