| Date: | 9–15 July |
| Edition: | 12th |
| Category: | ITF Women's Circuit |
| Location: | Contrexéville, France |
| Prize Money: | $100,000 |
| Champs: | Stefanie Vögele |
| Champd: |  An-Sophie Mestach /  Zheng Saisai |
The 2018 Grand Est Open 88 was a professional tennis tournament played on outdoor clay courts. It was the twelfth edition of the tournament and was part of the 2018 ITF Women's Circuit. It took place in Contrexéville, France, on 9–15 July 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 France | Pauline Parmentier | 63 | 1 | |
 Ukraine | Kateryna Kozlova | 67 | 2 | |
| Stefanie Vögele | 93 | 3 | ||
| Viktorija Golubic | 99 | 4 | ||
 Spain | Sara Sorribes Tormo | 102 | 5 | |
| Arantxa Rus | 105 | 6 | ||
| Belgium | Ysaline Bonaventure | 116 | 7 | |
| Mona Barthel | 118 | 8 |
The following players received a wildcard into the singles main draw:
The following players received entry from the qualifying draw:
Mandy Minella Mallaurie Noël Anastasiya Vasylyeva Lucie WargnierSee main article: 2018 Grand Est Open 88 – Singles.
Sara Sorribes Tormo, 6–4, 6–2See main article: 2018 Grand Est Open 88 – Doubles.
An-Sophie Mestach / Zheng Saisai def. 
Prarthana Thombare / Eva Wacanno, 3–6, 6–2, [10–7]