| Date: | 25 June–1 July |
| Edition: | 2nd |
| Category: | ITF Women's Circuit |
| Location: | Southsea, United Kingdom |
| Prize Money: | $100,000+H |
| Champs: |  Kirsten Flipkens |
| Champd: | Kirsten Flipkens /  Johanna Larsson |
| Before Name: | Aegon Southsea Trophy |
| Main Name: | Southsea Trophy |
The 2018 Fuzion 100 Southsea Trophy was a professional tennis tournament played on outdoor grass courts. It was the second edition of the tournament and was part of the 2018 ITF Women's Circuit. It took place in Southsea, United Kingdom, on 25 June–1 July 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Petra Martić | 45 | 1 | ||
| Belgium | Kirsten Flipkens | 48 | 2 | |
 Romania | Monica Niculescu | 59 | 3 | |
| Sweden | Johanna Larsson | 63 | 4 |
The following players received a wildcard into the singles main draw:
The following player received entry as an alternate:
See main article: article and 2018 Fuzion 100 Southsea Trophy – Singles.
Kirsten Flipkens def. 
Katie Boulter, 6–4, 5–7, 6–3See main article: article and 2018 Fuzion 100 Southsea Trophy – Doubles.
Kirsten Flipkens / Johanna Larsson def. 
Alicja Rosolska / 
Abigail Spears, 6–4, 3–6, [11–9]