| Date: | 18–24 June |
| Edition: | 4th |
| Category: | ATP Challenger Tour ITF Women's Circuit |
| Location: | Ilkley, United Kingdom |
| Prize Money: | €127,000 (ATP) $100,000 (ITF) |
| Champms: |  Sergiy Stakhovsky |
| Champmd: |  Austin Krajicek /  Jeevan Nedunchezhiyan |
| Champws: |  Tereza Smitková |
| Champwd: | Asia Muhammad / Maria Sanchez |
| Before Name: | Aegon Ilkley Trophy |
| After Name: | Ilkley Trophy |
| Main Name: | Ilkley Trophy |
The 2018 Fuzion 100 Ilkley Trophy was a professional tennis tournament played on outdoor grass courts. It was the fourth edition of the tournament and was part of the 2018 ATP Challenger Tour and the 2018 ITF Women's Circuit. It took place in Ilkley, United Kingdom, on 18–24 June 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Australia | Jordan Thompson | 95 | 1 | |
 Estonia | Jürgen Zopp | 107 | 2 | |
 Italy | Thomas Fabbiano | 111 | 3 | |
 Belarus | Ilya Ivashka | 115 | 4 | |
 Canada | Peter Polansky | 119 | 5 | |
| India | Ramkumar Ramanathan | 128 | 6 | |
| United States | Michael Mmoh | 132 | 7 | |
| Ukraine | Sergiy Stakhovsky | 133 | 8 |
The following players received wildcards into the singles main draw:
Jack Draper George Loffhagen Aiden McHugh Alexander WardThe following player received entry into the singles main draw as a special exempt:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Estonia | Kaia Kanepi | 43 | 1 | |
| Belinda Bencic | 61 | 2 | ||
 Thailand | Luksika Kumkhum | 94 | 3 | |
| Viktorija Golubic | 99 | 4 | ||
| Arantxa Rus | 100 | 5 | ||
| United States | Nicole Gibbs | 109 | 6 | |
 Russian Federation | Ekaterina Alexandrova | 110 | 7 | |
 Spain | Sara Sorribes Tormo | 114 | 8 |
The following players received a wildcard into the singles main draw:
The following players received entry from the qualifying draw:
The following player received entry as a Lucky Loser:
See main article: 2018 Fuzion 100 Ilkley Trophy – Men's singles.
Sergiy Stakhovsky def. Oscar Otte 6–4, 6–4.See main article: 2018 Fuzion 100 Ilkley Trophy – Women's singles.
Tereza Smitková def. Dayana Yastremska, 7–6(7–2), 3–6, 7–6(7–4)See main article: 2018 Fuzion 100 Ilkley Trophy – Men's doubles.
Austin Krajicek / Jeevan Nedunchezhiyan def. Kevin Krawietz / Andreas Mies 6–3, 6–3.See main article: 2018 Fuzion 100 Ilkley Trophy – Women's doubles.
Asia Muhammad / Maria Sanchez def. Natela Dzalamidze / 
Galina Voskoboeva, 4–6, 6–3, [10–1]
