| Champ: |  Coco Gauff |
| Runner: | Caty McNally |
| Score: | 1–6, 6–3, 7–6(7–1) |
| Before Name: | French Open – Girls' singles |
See main article: 2018 French Open.
Coco Gauff won the girls' singles tennis title at the 2018 French Open, defeating compatriot Caty McNally in the final, 1–6, 6–3, 7–6(7–1).
Whitney Osuigwe was the defending champion, but chose not to participate.