| Date: | 15–21 October |
| Edition: | 3rd |
| Category: | ATP World Tour 250 series |
| Prize Money: | €612,755 |
| Draw: | 28S / 16D |
| Surface: | Hard / indoor |
| Location: | Antwerp, Belgium |
| Champs: |  Kyle Edmund |
| Champd: |  Nicolas Mahut / Édouard Roger-Vasselin |
| Main Name: | European Open (tennis) European Open |
The 2018 European Open was a men's tennis tournament played on indoor hard courts. It was the third edition of the European Open and part of the ATP World Tour 250 series of the 2018 ATP World Tour. It took place at the Lotto Arena in Antwerp, Belgium, from October 15 to October 21.[1]
| width=70 | Country | width=175 | Player | Rank1 | Seed |
|---|---|---|---|---|---|
| United Kingdom | Kyle Edmund | 14 | 1 | ||
 Argentina | Diego Schwartzman | 16 | 2 | ||
 Canada | Milos Raonic | 20 | 3 | ||
| France | Richard Gasquet | 25 | 4 | ||
| France | Gilles Simon | 31 | 5 | ||
| France | Gaël Monfils | 37 | 6 | ||
| Frances Tiafoe | 40 | 7 | |||
| Robin Haase | 44 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Nikoloz Basilashvili → replaced by 
Yuki Bhambri
Roberto Carballés Baena → replaced by 
Salvatore Caruso
David Goffin → replaced by 
Jiří Veselý Stéphane Robert
Jozef Kovalík → replaced by Constant Lestienne| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
 Japan | Ben McLachlan | Jan-Lennard Struff | 43 | 1 | ||
| France | Nicolas Mahut | France | Édouard Roger-Vasselin | 44 | 2 | |
| Robin Haase | Matwé Middelkoop | 65 | 3 | |||
| India | Divij Sharan |  New Zealand | Artem Sitak | 75 | 4 |
The following pairs received wildcards into the doubles main draw:
See main article: 2018 European Open – Singles.
Kyle Edmund defeated Gaël Monfils, 3–6, 7–6(7–2), 7–6(7–4)See main article: 2018 European Open – Doubles.
Nicolas Mahut / Édouard Roger-Vasselin defeated 
Marcelo Demoliner / 
Santiago González, 6–4, 7–5
