The 2018 Erste Bank Open 500 was a men's tennis tournament played on indoor hard courts. It was the 44th edition of the event, and part of the ATP World Tour 500 Series of the 2018 ATP World Tour. It was held at the Wiener Stadthalle in Vienna, Austria, from 22 October until 28 October 2018. Second-seeded Kevin Anderson won the singles title.
| Event | W | F | SF | QF | Round of 16 | Round of 32 | width=85 | Q | width=85 | Q2 | width=85 | Q1 |
| Singles[1] | 500 | 300 | 180 | 90 | 45 | 0 | 20 | 10 | 0 | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Doubles | 0 | 45 | 25 | 0 |
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Dominic Thiem | 7 | 1 | ||
| Kevin Anderson | 8 | 2 | ||
| Grigor Dimitrov | 9 | 3 | ||
| John Isner | 10 | 4 | ||
| Kei Nishikori | 11 | 5 | ||
| Borna Ćorić | 13 | 6 | ||
| Fabio Fognini | 14 | 7 | ||
| Kyle Edmund | 15 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry as a special exempt:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Pablo Carreño Busta → replaced by 
Frances Tiafoe
Chung Hyeon → replaced by 
Andrey Rublev
Richard Gasquet → replaced by 
Cameron Norrie
Nick Kyrgios[2] → replaced by 
Nikoloz Basilashvili| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
 Austria | Oliver Marach | Mate Pavić | 5 | 1 | ||
 Poland | Łukasz Kubot |  Brazil | Marcelo Melo | 8 | 2 | |
 Colombia | Juan Sebastián Cabal | Colombia | Robert Farah | 15 | 3 | |
| United Kingdom | Jamie Murray | Brazil | Bruno Soares | 19 | 4 |
The following pairs received wildcards into the doubles main draw:
The following pair received entry from the qualifying draw:
The following pairs received entry as lucky losers:
See main article: 2018 Erste Bank Open – Singles.
Kei Nishikori, 6–3, 7–6(7–3)See main article: 2018 Erste Bank Open – Doubles.
Joe Salisbury / Neal Skupski defeated Mike Bryan / Édouard Roger-Vasselin, 7–6(7–5), 6–3
