| Date: | 22–28 January |
| Edition: | 8th |
| Category: | ITF Women's Circuit |
| Location: | Andrézieux-Bouthéon, France |
| Surface: | Hard / Indoor |
| Prize Money: | $60,000 |
| Champs: |  Georgina García Pérez |
| Champd: |  Ysaline Bonaventure / Bibiane Schoofs |
| Main Name: | Open Andrézieux-Bouthéon 42 |
The 2018 Engie Open Andrézieux-Bouthéon 42 was a professional tennis tournament played on indoor hard courts. It was the eighth edition of the tournament and was part of the 2018 ITF Women's Circuit. It took place in Andrézieux-Bouthéon, France, on 22–28 January 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 France | Pauline Parmentier | 82 | 1 | |
 Slovakia | Jana Čepelová | 110 | 2 | |
| Slovakia | Viktória Kužmová | 125 | 3 | |
| Arantxa Rus | 135 | 4 | ||
 Czech Republic | Tereza Martincová | 143 | 5 | |
| Antonia Lottner | 152 | 6 | ||
 Italy | Jasmine Paolini | 156 | 7 | |
 Poland | Magdalena Fręch | 163 | 8 |
The following players received a wildcard into the singles main draw:
The following players received entry from the qualifying draw:
See main article: 2018 Engie Open Andrézieux-Bouthéon 42 – Singles.
Georgina García Pérez def. Arantxa Rus, 6–2, 6–0 Ysaline Bonaventure / Bibiane Schoofs def. Camilla Rosatello / Kimberley Zimmermann, 4–6, 7–5, [10–7]