| Date: | 3–8 September |
| Edition: | 21st |
| Surface: | Yellow clay |
| Location: | Seville, Spain |
| Champs: |  Kimmer Coppejans |
| Champd: |  Gerard Granollers / Pedro Martínez |
The 2018 Copa Sevilla was a professional tennis tournament played on clay courts. It was the 21st edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Seville, Spain between 3 and 8 September 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Pedro Sousa | 116 | 1 | ||
| Yannick Maden | 125 | 2 | ||
 India | Ramkumar Ramanathan | 134 | 3 | |
 Argentina | Marco Trungelliti | 142 | 4 | |
 Norway | Casper Ruud | 143 | 5 | |
| Spain | Daniel Gimeno Traver | 155 | 6 | |
 Slovakia | Andrej Martin | 157 | 7 | |
| Spain | Enrique López Pérez | 159 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as a special exempt:
The following players received entry from the qualifying draw:
See main article: 2018 Copa Sevilla – Singles.
Kimmer Coppejans def. Alex Molčan 7–6(7–2), 6–1.See main article: 2018 Copa Sevilla – Doubles.
Gerard Granollers / Pedro Martínez def. Daniel Gimeno Traver / Ricardo Ojeda Lara 6–0, 6–2.
