| Date: | March 13–18 |
| Edition: | 12th |
| Category: | ATP Challenger Tour |
| Surface: | Hard (indoor) |
| Location: | Drummondville, Canada |
| Venue: | Tennis intérieur René-Verrier |
| Champs: |  Denis Kudla |
| Champd: |  Joris De Loore / Frederik Nielsen |
| Main Name: | Challenger de Drummondville |
The 2018 Challenger Banque Nationale de Drummondville was a professional tennis tournament played on indoor hard courts. It was the 12th edition of the tournament and part of the 2018 ATP Challenger Tour, offering a total of $75,000 in prize money. It took place in Drummondville, Canada between March 13 and March 18, 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Canada | Vasek Pospisil | 75 | 1 | |
| Henri Laaksonen | 125 | 2 | ||
 France | Gleb Sakharov | 158 | 3 | |
 United Kingdom | Liam Broady | 164 | 4 | |
| Denis Kudla | 168 | 5 | ||
| Canada | Filip Peliwo | 186 | 6 | |
| Evan King | 200 | 7 | ||
| Canada | Brayden Schnur | 202 | 8 |
The following players received wildcards into the singles main draw:
Pavel Krainik Jack Mingjie Lin Samuel Monette Benjamin SigouinThe following players entered the singles main draw with a protected ranking:
The following players received entry as alternates:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
JC Aragone Jared HiltzikSee main article: 2018 Challenger Banque Nationale de Drummondville – Singles.
Denis Kudla def. Benjamin Bonzi, 6–0, 7–5See main article: 2018 Challenger Banque Nationale de Drummondville – Doubles.
Joris De Loore / Frederik Nielsen def. 
Luis David Martínez / Filip Peliwo, 6–4, 6–3
