| Champ: |  Elina Svitolina |
| Runner: |  Aliaksandra Sasnovich |
| Score: | 6–2, 6–1 |
| Draw: | 30 (4 / 2) |
| Seeds: | 8 |
| Before Name: | Brisbane International – Women's singles |
| After Name: | Brisbane International – Women's singles |
See main article: 2018 Brisbane International.
Karolína Plíšková was the defending champion, but lost in the semifinals to Elina Svitolina.
Svitolina went on to win the title, defeating Aliaksandra Sasnovich in the final, 6–2, 6–1.
Garbiñe Muguruza was in contention for the WTA No. 1 singles ranking at the start of the tournament, but she retired during her opening second round match.[1] As such, Simona Halep retained the No. 1 ranking. Of note, if was the fourth consecutive edition of the tournament that Muguruza had to retire or withdraw from due to injury.[2]
The top two seeds received a bye into the second round.