| Date: | 16–22 July |
| Edition: | 1st |
| Category: | ITF Women's Circuit |
| Location: | Berkeley, United States |
| Prize Money: | $60,000 |
| Champs: |  Sofia Kenin |
| Champd: | Nicole Gibbs / Asia Muhammad |
The 2018 Berkeley Tennis Club Challenge was a professional tennis tournament played on outdoor hard courts. It was the first edition of the tournament and was part of the 2018 ITF Women's Circuit. It took place in Berkeley, United States, on 16–22 July 2018.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| United States | Sofia Kenin | 76 | 1 | |
| United States | Nicole Gibbs | 113 | 2 | |
 Japan | Nao Hibino | 119 | 3 | |
| United States | Kristie Ahn | 147 | 4 | |
| United States | Jamie Loeb | 158 | 5 | |
| United States | Grace Min | 172 | 6 | |
| United States | Francesca Di Lorenzo | 192 | 7 | |
| Japan | Mayo Hibi | 197 | 8 |
The following players received a wildcard into the singles main draw:
The following players received entry from the qualifying draw:
Haruna Arakawa Lorraine Guillermo Connie Ma Pamela MontezSee main article: 2018 Berkeley Tennis Club Challenge – Singles.
Sofia Kenin def. Nicole Gibbs, 6–0, 6–4See main article: 2018 Berkeley Tennis Club Challenge – Doubles.
Nicole Gibbs / Asia Muhammad def. 
Ellen Perez / Sabrina Santamaria, 6–4, 6–1