| Champ: | Liang En-shuo |
| Runner: |  Clara Burel |
| Score: | 6–3, 6–4 |
See main article: 2018 Australian Open.
Liang En-shuo won the girls' singles title at the 2018 Australian Open, defeating Clara Burel in the final, 6–3, 6–4.
Marta Kostyuk was the defending champion, but withdrew as she was still competing in the women's tournament.