| Club: | Lecce |
| Season: | 2018–19 |
| Manager: | Fabio Liverani |
| Chairman: | Saverio Sticchi Damiani |
| Chrtitle: | President |
| Stadium: | Stadio Via del Mare |
| League: | Serie B |
| League Result: | 2nd (promoted) |
| Cup1: | Coppa Italia |
| Cup1 Result: | Third round |
| League Topscorer: | Andrea La Mantia (17) |
| Season Topscorer: | Andrea La Mantia (17) |
| Highest Attendance: | 25,135 vs Spezia (11 May 19) |
| Lowest Attendance: | 5,438 vs Feralpisalò (7 Aug 18) |
| Prevseason: | 2017–18 |
| Nextseason: | 2019–20 |
The 2018–19 season is U.S. Lecce's first season in Serie B since 2010 after their relegation from Serie A to Lega Pro at the end of the 2011–12 season. The club competes in Serie B and the Coppa Italia.[jago][seun]
.[1] Players in italics left the club during the season.
Players with a * joined the club during the season.
** Left the club (shirt no. 9) on loan in August 2019, but came back from loan in January 2019.
*** from the Primavera team.