| Year: | 2018–19 |
| Team: | USC Trojans |
| Sport: | basketball |
| Conference: | Pac-12 Conference |
| Short Conf: | Pac-12 |
| Record: | 16–17 |
| Conf Record: | 8–10 |
| Head Coach: | Andy Enfield |
| Hc Year: | 6th |
| Asst Coach1: | Jason Hart |
| Ac1 Year: | 6th |
| Asst Coach2: | Chris Capko |
| Ac2 Year: | 3rd |
| Asst Coach3: | Eric Mobley |
| Ac3 Year: | 1st |
| Arena: | Galen Center |
The 2018–19 USC Trojans men's basketball team represented the University of Southern California during the 2018–19 NCAA Division I men's basketball season. Led by sixth-year head coach Andy Enfield, they played their home games at the Galen Center in Los Angeles, California as members of the Pac-12 Conference.
The Trojans finished the season 24–12, 12–6 in Pac-12 play to finish in second place. As the No. 2 seed in the Pac-12 tournament, they defeated Oregon State in the quarterfinals and Oregon in the semifinals before losing to Arizona in the championship game. They were one of the last four teams not selected for the NCAA tournament and as a result earned a No. 1 seed in the National Invitation Tournament, where they defeated UNC Asheville in the first round before losing to Western Kentucky in the second round.
| Name | Pos. | Height | Weight | Year | Hometown | Reason for Departure | |
|---|---|---|---|---|---|---|---|
| G | 195 | Northbrook, Illinois | Graduated | ||||
| G | 195 | Deridder, Louisiana | Graduated | ||||
| G | 185 | Etiwanda, California | Graduated | ||||
| F | 225 | Lawndale, California | Declared for 2018 NBA draft[1] | ||||
| F | 225 | Dallas, Texas | Transferred[2] |
|-!colspan=9 style=| Non-conference regular season|-!colspan=9 style=| Pac-12 regular season|-!colspan=9 style=| Pac-12 tournament