| Club: | Viktoria Plzeň |
| Season: | 2018–19 |
| Chrtitle: | President |
| Chairman: | Adolf Šádek |
| Mgrtitle: | Head coach |
| Manager: | Pavel Vrba |
| Stadium: | Doosan Arena |
| League: | Czech First League |
| League Result: | 2nd |
| Cup1: | Czech Cup |
| Cup1 Result: | Round of 16 |
| Cup2: | UEFA Champions League |
| Cup2 Result: | Group stage |
| Cup3: | Europa League |
| Cup3 Result: | Round of 32 |
| League Topscorer: | Michael Krmenčík (7) |
| Season Topscorer: | Michael Krmenčík (9) |
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| Prevseason: | 2017–18 |
| Nextseason: | 2019–20 |
The 2018–19 season is FC Viktoria Plzeň's 26th season in the Czech First League. The team is competing in Czech First League, the Czech Cup, and the UEFA Champions League.
Pavel Vrba returned to manage the club in the summer of 2017. He had previously served as manager from 2008 to 2013 before leaving to manage the national team.
| Date | Player | Moving from | Fee | |||
|---|---|---|---|---|---|---|
 Ubong Moses Ekpai |  FC Fastav Zlín | Undisclosed | ||||
| Luděk Pernica | FK Jablonec | Undisclosed | ||||
 Roman Procházka |  PFC Levski Sofia | Free | ||||
| Dominik Janošek | 1. FC Slovácko | Undisclosed | ||||
| Ondřej Štursa | FC Viktoria Plzeň | Free | ||||
| Tomáš Poznar | FC Baník Ostrava | Loan Return | ||||
| Jakub Řezníček | SK Sigma Olomouc | Loan Return | ||||
| Jan Suchan | FK Senica | Loan Return | ||||
| Jakub Šiman | TJ Jiskra Domažlice | Loan Return | ||||
| Jiří Piroch | FK Jablonec | Loan Return | ||||
 Erik Janža |  Pafos FC | Loan Return | ||||
| Václav Pilař | FC Slovan Liberec | Loan Return | ||||
| Pavel Bucha | SK Slavia Prague | Free |
| Date | Player | Moving from | Fee | |||
|---|---|---|---|---|---|---|
 Andreas Ivanschitz | Unknown | Free | ||||
| Dominik Janošek | 1. FC Slovácko | Loan | ||||
| Václav Pilař | SK Sigma Olomouc | Undisclosed | ||||
| Jiří Piroch | MFK Karviná | Loan | ||||
| Jan Suchan | MFK Karviná | Loan | ||||
| Ondřej Štursa | Dukla Prague | Loan | ||||
| Tomáš Poznar | FC Fastav Zlín | Free | ||||
| Erik Janža | NK Osijek | Undisclosed | ||||
| Marek Bakoš | FC Spartak Trnava | Loan | ||||
| Diego Živulić | Pafos FC | Undisclosed | ||||
| Jakub Šiman | Olympia Radotín | Undisclosed | ||||
| Petr Bolek | Free agent | None |
See main article: 2018–19 Czech First League.
See main article: 2018–19 Czech Cup.
See main article: 2018–19 UEFA Champions League.
See main article: 2018–19 UEFA Champions League group stage.
See main article: 2018–19 UEFA Europa League.
See main article: 2018–19 UEFA Europa League knockout phase.