The 2017 U.S. Men's Clay Court Championships (also known as the Fayez Sarofim & Co. U.S. Men's Clay Court Championships for sponsorship purposes) was a tennis tournament played on outdoor clay courts. It was 49th edition of the U.S. Men's Clay Court Championships, and an ATP World Tour 250 event on the 2017 ATP World Tour. It took place at River Oaks Country Club in Houston, Texas, United States, from April 10 through April 16, 2017.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Jack Sock | 15 | 1 | ||
| John Isner | 23 | 2 | ||
| Sam Querrey | 25 | 3 | ||
| Steve Johnson | 29 | 4 | ||
 Spain | Fernando Verdasco | 31 | 5 | |
| Spain | Feliciano López | 36 | 6 | |
| Donald Young | 42 | 7 | ||
 Brazil | Thomaz Bellucci | 67 | 8 |
The following players received wildcards into the main draw:
The following player using a protected ranking into the singles main draw:
The following players received entry via the qualifying draw:
Adrian Mannarino → replaced by 
Nicolás Kicker| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| Bob Bryan | Mike Bryan | 6 | 1 | |||
 Colombia | Juan Sebastián Cabal | Colombia | Robert Farah | 64 | 2 | |
| Julio Peralta | Argentina | Horacio Zeballos | 94 | 4 |
The following pairs received wildcards into the doubles main draw:
The following pair received entry as alternates:
See main article: 2017 U.S. Men's Clay Court Championships – Singles.
Steve Johnson def. Thomaz Bellucci, 6–4, 4–6, 7–6(7–5)See main article: 2017 U.S. Men's Clay Court Championships – Doubles.
Horacio Zeballos def. Dustin Brown / Frances Tiafoe, 4–6, 7–5, [10–6]