| Champ: |  Kristina Mladenovic |
| Runner: |  Yulia Putintseva |
| Score: | 6–2, 6–7(3–7), 6–4 |
| Draw: | 24 (4 / 2) |
| Seeds: | 8 |
| Before Name: | St. Petersburg Ladies' Trophy – Singles |
| After Name: | St. Petersburg Ladies' Trophy – Singles |
| Type: | singles doubles |
See main article: 2017 St. Petersburg Ladies' Trophy.
The 2017 St. Petersburg Ladies' Trophy – Singles season began with Roberta Vinci (defending champion from the previous year) losing out in the quarterfinals to unseeded Kristina Mladenovic.
Mladenovic went on to win the season and achieve her first WTA singles title, defeating Yulia Putintseva in the final, 6–2, 6–7(3–7), 6–4.
The top four seeds received a bye into the second round.