| Date: | 15 – 20 May |
| Edition: | 21st |
| Draw: | 32S / 16D |
| Surface: | Clay |
| Location: | Samarkand, Uzbekistan |
| Champs: |  Adrián Menéndez Maceiras |
| Champd: |  Laurynas Grigelis /  Zdeněk Kolář |
The 2017 Samarkand Challenger was a professional tennis tournament played on clay courts. It was the 21st edition of the tournament which was part of the 2017 ATP Challenger Tour. It took place in Samarkand, Uzbekistan between 15 and 20 May 2017.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Ukraine | Sergiy Stakhovsky | 96 | 1 | |
 Russian Federation | Teymuraz Gabashvili | 151 | 2 | |
| Jason Jung | 167 | 3 | ||
| Spain | Adrián Menéndez Maceiras | 177 | 4 | |
| Michael Mmoh | 183 | 5 | ||
 Belgium | Joris De Loore | 190 | 6 | |
 Serbia | Nikola Milojević | 191 | 7 | |
 Kazakhstan | Dmitry Popko | 203 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as a special exempt:
The following players received entry from the qualifying draw:
See main article: 2017 Samarkand Challenger – Singles.
Adrián Menéndez Maceiras def. 
Aldin Šetkić 6–4, 6–2.See main article: 2017 Samarkand Challenger – Doubles.
Laurynas Grigelis / Zdeněk Kolář def. 
Prajnesh Gunneswaran / Vishnu Vardhan 7–6(7–2), 6–3.
